Simparica Trio (Sarolaner, Moxidectin, Pyrantel)
Simparica
Disclaimer
Product images are shown for reference only and may not reflect the exact packaging or appearance of the medication you receive. Brand-name medications may vary in appearance based on country-specific packaging and labeling requirements. These appearance differences do not affect the prescribed active ingredient, strength, or dosage form being dispensed. Canada Drugs Online works with licensed pharmacies that follow strict standards for dispensing accuracy, medication quality, and patient safety. Please see our Medication Safety Standards for more information.

Simparica Trio (Sarolaner, Moxidectin, Pyrantel)

Prescription Required

Currently Unavailable

This medication is not available to order online at this time. Availability may change. Contact our support team if you have questions about this product or need help with your order. You can still review safety information, FAQs, related medications, and clinical references below.

Contact Us About Availability
Pricing & Ordering Pricing How It Works How It Works Safety & Clinical Safety FAQs FAQs Trust & Policies Trust Related Medications Related

How Simparica Trio Fulfillment Works

1. Select Product

Find the exact dosage to match your valid prescription.

2. Submit Rx

Securely upload a photo of your U.S. prescription.

3. Clinical Review

Our licensed staff strictly verify the prescription.

4. Doorstep Delivery

Shipped in discreet manufacturer packaging.

Included In Your Simparica Trio Order

Sealed manufacturer packaging
Prescribed directions for Simparica Trio
Simparica Trio patient safety leaflet
Itemized invoice for your order
Clinical Accuracy Review | Information reviewed for accuracy and aligned with trusted medical sources. Learn more about our content standards

Simparica Trio Safety and Prescribing Information

About Simparica Trio

Medication class: Antiparasitic
Simparica Trio is an antiparasitic medication used for the prevention and treatment of flea and tick infestations, as well as intestinal parasites in dogs. It combines three active ingredients: Sarolaner, Moxidectin, and Pyrantel.
Safety Information
Monitor your pet for any adverse reactions after administration. Seek immediate veterinary assistance if severe side effects occur.
Precautions
Use with caution in dogs with a history of seizures. Always consult your veterinarian before starting treatment, especially in pregnant or nursing dogs.
Common Side Effects
Common side effects include vomiting, diarrhea, lethargy, and loss of appetite. These effects are usually mild and transient.
Serious Side Effects
Severe side effects may include seizures, severe allergic reactions, or persistent vomiting. Contact your veterinarian if these occur.
Dosage & Administration
Administer Simparica Trio with food to enhance absorption. Ensure your pet is calm during administration for a smoother experience.
Drug Interactions
Simparica Trio may interact with other medications such as Amitraz, Ivermectin, and Milbemycin. Always inform your veterinarian of all medications your pet is taking.
Alternatives
Alternatives to Simparica Trio include Bravecto, NexGard, and Advantage Multi, which also provide protection against fleas and ticks.
Pregnancy & Lactation
The safety of Simparica Trio in pregnant or nursing dogs has not been established. Consult your veterinarian for guidance.
Storage Information
Store Simparica Trio at room temperature, away from moisture and heat to maintain its effectiveness.
Overdose Management
In case of overdose, contact your veterinarian immediately for guidance on the appropriate steps to take.
Travel Considerations
When traveling, keep Simparica Trio in its original packaging to ensure proper labeling and dosage information.

Simparica Trio FAQ

How should I administer Simparica Trio to my pet, and are there any specific preparation steps I need to follow?
Administer Simparica Trio orally with food for better absorption. Ensure your pet is calm and comfortable during administration.
What should I do if I miss a dose of Simparica Trio for my pet?
Give the missed dose as soon as you remember, but skip it if it's close to the next scheduled dose. Do not double up.
Are there any common side effects I should watch for after giving my pet Simparica Trio?
Common side effects include vomiting, diarrhea, lethargy, and loss of appetite. Monitor your pet closely after administration.
Can Simparica Trio be safely used in pregnant or nursing pets?
The safety of Simparica Trio in pregnant or nursing dogs has not been established, so consult your veterinarian before use.
What should I discuss with my veterinarian before starting my pet on Simparica Trio?
Discuss your pet's health history, any medications they are currently taking, and any previous reactions to similar treatments.

Clinical Integrity

Canada Drugs Online is committed to upholding rigorous standards for medication safety, product integrity, and fulfillment quality.

Our network includes licensed pharmacy partners and regulated international fulfillment providers that follow applicable dispensing, storage, and quality assurance requirements in their jurisdiction. Each order is processed only after a valid prescription is received and reviewed, with established controls in place to support accuracy, proper medication handling, and patient safety.

Prescription Policy

We maintain a zero-exception requirement for valid U.S. prescriptions.
  • Valid prescription required for all Simparica Trio orders.
  • All orders reviewed for compliance.
  • Strength, form, and quantity must align.
  • Patient and prescription details must match.
  • Altered or invalid prescriptions not accepted.
Review Full Policy

Our Service Commitment

Our service commitment is a promise of accuracy, careful handling, and dependable service for every Simparica Trio order placed through Canada Drugs Online.

From order processing to fulfillment coordination, we work to help ensure your Simparica Trio order is handled with care and clear attention to accuracy.
Place an order by phone: 1-888-868-1920
Medical Disclaimer: The clinical information provided on this page is for educational purposes only and does not constitute medical advice. You should always consult with your prescribing physician or a qualified healthcare professional regarding any questions you have about your medical condition or treatment plan. Fast facts and summaries are not a substitute for professional medical judgment.

Clinical References